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WAY 163909
CAS No. 428868-32-0
WAY 163909 ( WAY163909;WAY-163909 )
产品货号. M14454 CAS No. 428868-32-0
A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
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| 50MG | ￥16038 | 有现货 |
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| 100MG | ￥20250 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称WAY 163909
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM.
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产品描述A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM, >20-fold selectivity over 5-HT2A and 5-HT2B receptor subtypes (IC50=212 and 485 nM, respectively); stimulates the mobilization of intracellular calcium in CHO cells stably expressing the human 5-HT2C with EC50 of 8 nM; produces a dose-dependent reduction in food intake in rat (ED50=2.93 mg/kg), also exhibits preclinical antipsychotic-like activity in vivo.
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同义词WAY163909;WAY-163909
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域Cancer
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适应症——
化学信息
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CAS Number428868-32-0
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分子量214.31
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分子式C14H18N2
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纯度>98% (HPLC)
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溶解度——
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SMILES[H][C@]1(CCC[C@]21[H])N3CCNCC4=C3C2=CC=C4
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化学全称(11R,15R)-7,10-diazatetracyclo[8.5.1.0^{5,16}.0^{11,15}]hexadeca-1,3,5(16)-triene
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Dunlop J, et al. J Pharmacol Exp Ther. 2005 May;313(2):862-9.
2. Marquis KL, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):486-96.
3. Rosenzweig-Lipson S, et al. Psychopharmacology (Berl). 2007 Jun;192(2):159-70.
4. Grauer SM, et al. Psychopharmacology (Berl). 2009 May;204(1):37-48.
2. Marquis KL, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):486-96.
3. Rosenzweig-Lipson S, et al. Psychopharmacology (Berl). 2007 Jun;192(2):159-70.
4. Grauer SM, et al. Psychopharmacology (Berl). 2009 May;204(1):37-48.
产品手册
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